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Fission (n.) A method of asexual reproduction among the lowest (unicellular) organisms by means of a process of self-division, consisting of gradual division or cleavage of the into two parts, each of which then becomes a separate and independent organisms; as when a cell in an animal or plant, or its germ, undergoes a spontaneous division, and the parts again subdivide. See Segmentation, and Cell division, under Division.